| Cheeca Lodge & Spa | 81801 Overseas Hwy, Islamorada | $99 - 715 |
| Comfort Inn | 3824 North Roosevelt Blvd., Key West | $70 - 670 |
| Crowne Plaza La Concha Hotel | 430 Duval Street, Key West | $110 - 670 |
| Days Inn Key West | 3852 N Roosevelt, Key West | $70 - 270 |
| Fairfield Inn Key West | 2400 N Roosevelt Blvd., Key West | $76 - 115 |
| Hilton Resort & Marina Hotel | 245 Front Street, Key West | $165 - 499 |
| Holiday Inn Beachside | 3841 North Roosevelt Blvd., Key West | $90 - 449 |
| Holiday Inn Key Largo | 99701 Overseas Highway, Key Largo | $100 - 270 |
| Holiday Inn Resort & Marina | 13201 Overseas Hwy. Mm 54, Marathon | $86 - 420 |
| Howard Johnson Resort Hotel | Bayside At Mm 102 Overseas Hwy, Key Largo | $60 - 260 |
| Hyatt Regency Key West Resort Hotel | 601 Front Street, Key West | $250 - 563 |
| Lime Tree Bay Resort Hotel | 68500 Overseas Hwy., Layton Long Key | $130 - 168 |
| Marriott Bay Beach Resort Hotel | 103800 Overseas Highway, Key Largo | $150 - 158 |
| Marriott Courtyard On The Gulf Hotel | 3420 N Roosevelt Blvd, Key West | $23 - 410 |
| Ocean Key Resort Hotel | Zero Duval Street, Key West | $260 - 407 |
| Quality Inn & Suites | 3850 N Roosevelt Boulevard, Key West | $90 - 460 |
| Radisson Hotel Key West | 3820 Roosevelt Road, Key West | $99 - 499 |
| Ramada Limited Hotel | 99751 Overseas Highway, Key Largo | $100 - 180 |
| Ramada Marathon Oceanview Hotel | 13351 Overseas Highway, Marathon | $86 - 272 |
| The Gardens Hotel | 526 Angela Street, Key West | $205 - 400 |
Popular hotels nearby Duck Keys:
